FINAL_OM-IR-2026_Report-PDF-Version_Pages-Compressed - Flipbook - Page 38
Scaling Innovation that Changes Lives
Spotlight: Accelerator Companies
Translating Innovation Into Real-World
Applications
Ampa Health: Achieving Remission
One Mind Accelerator has been part of
in a Single Day Instead of Weeks
Ampa’s trajectory since its early days,
Depression has long been treated as a
supporting fundraising and opening doors
condition to manage. Ampa Health is
with payors and providers that helped bring
treating it as one to cure — fast.
the technology to clinical scale. Ampa’s goal
from here: achieving one billion remissions –
In February 2025, the Ampa One system, a
which, given the trajectory of success,
portable brain stimulation device for treating
is within the realm of possibility.
depression, received FDA clearance for
major depressive disorder in adults who
Somethings: Meeting Teens in the
haven’t responded to prior antidepressants.
Moments That Matter
In June, Ampa emerged from stealth to raise
Somethings is a digital mental health
$8.5M in an oversubscribed Pre-A round
platform that connects teens and young
led by Nexus NeuroTech Ventures. Four
adults with certi昀椀ed peer specialist mentors
months later, Ampa launched its nationwide
— young adults with lived experience —
commercial rollout.
who are available on demand, with no
o昀케ce hours, via text and video, and
Ampa is pioneering a protocol that
supported by licensed clinical supervisors.
compresses what once required 36 clinic
The platform serves teens in their moments
visits over multiple weeks into a single day –
of crisis, without making them wait for
delivering a 60% remission rate, well ahead
an appointment.
of conventional antidepressant benchmarks.
The system is now deployed at more than
One Mind Accelerator has backed
100 sites – including Kaiser Permanente,
Somethings since its inaugural 2023 cohort,
Amen Clinics, and the U.S. Army – reaching
helping the company build the foundations
over 100 patients per week.
that would enable it to partner with North
ONE MIND
2025 Annual Impact Report
